The effects of wine consumption on lipid profile

The effects of wine consumption on the lipid profile were analysed in a study published in the Journal of Health and Aging. The researchers distinguished between triglycerides, total cholesterol, LDL, HDL and fibrinogen.
The MEDLINE (via PubMed), Scopus, Cochrane, and Web of Science databases were examined to conduct a systematic review and meta-analysis.
Thirty-three studies were included in this systematic review, and 29 were included in the meta-analysis. The pooled effect size (ES) for the effect of red wine consumption on the different lipid profile parameters was significant only for the effect of red wine on the LDL parameter in the before and after studies (-0.29 (95% CI -0.54, -0.05)). The pooled ES for the effect of white wine in before and after studies and clinical trials for the effect of wine consumption on the different parameters did not show any significant results.
This systematic review and meta-analysis revealed that wine consumption has an effect on reducing LDL and has no effect on total cholesterol, HDL, triglycerides, or fibrinogen. This research revealed that the duration of the intervention affects triglyceride and total cholesterol levels, indicating that longer interventions are more effective for these two parameters.
Source: Lucerón-Lucas-Torres M, Ruiz-Grao MC, Cavero-Redondo I, di Lorenzo C, Pascual-Morena C, Priego-Jiménez S, Gómez-Guijarro D, Álvarez-Bueno C. The effects of wine consumption and lipid profile: A systematic review and meta-analysis of clinical trials. J Nutr Health Aging. 2025 Mar 22;29(6):100539.