The effects of moderate alcohol consumption on circulating metabolites and gut microbiota in patients with coronary artery disease

Epidemiological studies confirm that moderate alcohol consumption was associated with a reduced risk of adverse cardiovascular events. The authors of a paper published in the journal Frontiers in Cardiovascular Medicine state that it is increasingly recognized that the composition of gut microbiota and metabolites is involved in modulating the cardiovascular health of the host. However, the association of moderate alcohol consumption with serum metabolites and gut microbiome and its impact on coronary artery disease (CAD) is not fully investigated.
The study reveals that the impact of moderate alcohol consumption on serum metabolites and gut microbiota in patients with CAD seem to be separated from that of heavy and non-alcohol consumption. Moderate drinking tend to have more positive effects on metabolic profiles and commensal flora, which may explain its beneficial effects on cardiovascular health. Overall, the study provides a novel insight into the effects of moderate alcohol consumption in patients with CAD.
Source: Zhao X, Zhou R, et al. The Effects of Moderate Alcohol Consumption on Circulating Metabolites and Gut Microbiota in Patients With Coronary Artery Disease. Front Cardiovasc Med. 2021 Nov 2;8:767692.