Resveratrol regulates inflammation and improves oxidative stress via Nrf2 signalling pathway

Usually, in aerobic metabolism, natural materials including nucleic acids, proteins, and lipids can experience auxiliary injury by oxidative responses. This damage produced by reactive oxygen/nitrogen species has been identified as “oxidative stress.” As a natural polyphenol found in red wine and peanuts, resveratrol is one of the most eminent anti-aging mixtures. Based on many studies, resveratrol hinders destructive effects of inflammatory causes and reactive oxygen radicals in several tissues. The nuclear erythroid 2-related factor 2 (Nrf2) is a factor related to transcription with anti-inflammatory, anti-oxidant possessions which is complicated by enzyme biotransformation and biosynthesis of lipids and carbohydrates.
A review published in the journal Phytotherapy Research, provides current understanding and information about the character of resveratrol against oxidative stress and regulation of inflammation via Nrf2 signalling pathway.
Source: Shahcheraghi, S. H., Salemi, F., Small, S., Syed, S., Salari, F., Alam, W., Cheang, W. S., Saso, L., & Khan, H. (2023). Resveratrol regulates inflammation and improves oxidative stress via Nrf2 signaling pathway: Therapeutic and biotechnological prospects. Phytotherapy Research, 1– 16.