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Lifestyle behaviour in the Seguimiento Universidad De Navarra (SUN) Cohort linked to lower risk of diabetes
A d study lead by Liz Ruiz-Estigarribia prospectively assessed the association between a healthy lifestyle score (HLS) and the risk of type 2 diabetes mellitus.
11,005 participants initially free of diabetes diagnosis in the SUN cohort were followed in the study. Only one incident case of type 2 diabetes mellitus was found among those with a baseline BMI ≤22 kg/m2. The analysis was therefore restricted to participants with a baseline BMI >22 kg/m2. The researchers evaluated the influence of lifestyle-related factors based on the same 10-point healthy lifestyle score.
Incident cases of type 2 diabetes mellitus were self-reported by participants and confirmed by a physician. Cox proportional-hazards regression models were fitted to assess the association between healthy lifestyle score and the incidence of type 2 diabetes mellitus. After a median follow-up of 12 years, 145 incident cases of type 2 diabetes mellitus were observed. Among participants with a BMI >22 kg/m2, the highest category of healthy lifestyle score adherence (7-9 points) showed a significant 46% relatively decreased hazard of type 2 diabetes mellitus compared with the lowest category (0-4 points) (multivariable adjusted HR: 0.54; 95% CI: 0.30-0.99).
The authors conclude that a higher adherence to a healthy lifestyle score, based on the 10 point score which includes some factors not typically studied, may reduce type 2 diabetes mellitus risk. Further, they suggest that preventive efforts should preferentially focus on weight control, but this score may promote a comprehensive approach to diabetes prevention beyond weight reduction.
Source: Liz Ruiz-Estigarribia, Miguel A. Martínez-González, Jesús Díaz-Gutiérrez, Carmen Sayón-Orea, Francisco J. Basterra-Gortari, Maira Bes-Rastrollo, Lifestyle behavior and the risk of type 2 diabetes in the Seguimiento Universidad de Navarra (SUN) cohort, Nutrition, Metabolism and Cardiovascular Diseases, 2020, ISSN 0939-4753.
11,005 participants initially free of diabetes diagnosis in the SUN cohort were followed in the study. Only one incident case of type 2 diabetes mellitus was found among those with a baseline BMI ≤22 kg/m2. The analysis was therefore restricted to participants with a baseline BMI >22 kg/m2. The researchers evaluated the influence of lifestyle-related factors based on the same 10-point healthy lifestyle score.
Incident cases of type 2 diabetes mellitus were self-reported by participants and confirmed by a physician. Cox proportional-hazards regression models were fitted to assess the association between healthy lifestyle score and the incidence of type 2 diabetes mellitus. After a median follow-up of 12 years, 145 incident cases of type 2 diabetes mellitus were observed. Among participants with a BMI >22 kg/m2, the highest category of healthy lifestyle score adherence (7-9 points) showed a significant 46% relatively decreased hazard of type 2 diabetes mellitus compared with the lowest category (0-4 points) (multivariable adjusted HR: 0.54; 95% CI: 0.30-0.99).
The authors conclude that a higher adherence to a healthy lifestyle score, based on the 10 point score which includes some factors not typically studied, may reduce type 2 diabetes mellitus risk. Further, they suggest that preventive efforts should preferentially focus on weight control, but this score may promote a comprehensive approach to diabetes prevention beyond weight reduction.
Source: Liz Ruiz-Estigarribia, Miguel A. Martínez-González, Jesús Díaz-Gutiérrez, Carmen Sayón-Orea, Francisco J. Basterra-Gortari, Maira Bes-Rastrollo, Lifestyle behavior and the risk of type 2 diabetes in the Seguimiento Universidad de Navarra (SUN) cohort, Nutrition, Metabolism and Cardiovascular Diseases, 2020, ISSN 0939-4753.
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