Dose-response analysis between alcohol consumption and psoriasis

The association between psoriasis and alcohol consumption has been inconsistent across various studies. However, the authors of a study that they aren’t aware of any dose-response meta-analysis having been performed to date. Their study investigated the association between alcohol consumption and psoriasis.
A search was performed using Embase and MEDLINE. 3,904 studies were identified, of which 48 studies with 1,702,847 individuals across 24 countries were included.
Alcohol consumption was positively associated with psoriasis (odds ratio [OR], 1.47; 95% confidence interval [CI], 1.27-1.70). In addition, a significantly increased OR for psoriasis was observed in males (OR, 1.84; 95% CI, 1.13-3.01) but not in females (OR, 1.22; 95% CI, 0.97-1.54). Based on eight studies, including three cohort and five case-control studies, the analysis revealed that with each additional gram of daily alcohol intake, the OR for psoriasis increased by 4%.
The researchers found a positive association between alcohol consumption and psoriasis. The association is more prominent in the group drinking more than 45 g of alcohol per day (3.2 alcoholic drink equivalent).
Source: Choi J, Han I, Min J, Yun J, Kim BS, Shin K, Kim K, Kim YH. Dose-response analysis between alcohol consumption and psoriasis: A systematic review and meta-analysis. J Dtsch Dermatol Ges. 2024 Apr 28.