Association between alcohol consumption and incidence of type 2 diabetes in middle-aged Japanese from Panasonic cohort study 12

A retrospective cohort study investigated the association between alcohol consumption and the onset of type 2 diabetes in middle-aged Japanese individuals.
Participants were aged 40 and above from Panasonic Corporation, Osaka, Japan’s medical health check up program from 2008 to 2021. Researchers assessed the association between alcohol consumption and the onset of type 2 diabetes. The total and median follow-up duration was 13 years and 7 (3-13) years (748,090 person-years).
Among 102,802 participants, 7,510 participants (7.3%) developed type 2 diabetes during the study period. Alcohol consumption at the level of 0 < to < 22 g/day and 22 to < 39 g/day were negatively associated with developing type 2 diabetes compared to complete alcohol abstainers. Alcohol consumption at levels of 39 to < 66 g/day and at levels of ≥ 66 g/day were positively associated with developing type 2 diabetes in participants with BMI < 25 kg/m2.
All levels of alcohol consumption were negatively associated with developing type 2 diabetes in participants with BMI ≥ 25 kg/m2. Moderate-to-heavy alcohol consumption were positively associated with developing type 2 diabetes for participants with BMI < 25 kg/m2, whereas alcohol intake was nega-tively associated with developing type 2 diabetes among participants with BMI ≥ 25 kg/m2.
Source: Takahashi, F., Okada, H., Hashimoto, Y. et al. Association between alcohol consumption and incidence of type 2 diabetes in middle-aged Japanese from Panasonic cohort study 12. Sci Rep 14, 20315 (2024).