Associations between alcohol consumption and anxiety, depression, and health-related quality of life in colorectal cancer survivors
Alcohol consumption is a major risk factor for colorectal cancer (CRC). It is currently poorly understood, however, how alcohol and different alcoholic beverage types are related to psychosocial out-comes in CRC survivors.
A study included 910 CRC survivors from the pooled EnCoRe and PROCORE cohorts. Longitudinal associations of alcohol consumption, including consumption of beer, wine, and liquor, with anxiety, depression, and health-related quality of life (HRQoL) were examined while correcting for sociodemo-graphic, lifestyle, and clinical factors.
Survivors were on average 67 years and 37% was female. In the first 2 years post-diagnosis, survivors who consumed more alcoholic drinks/week reported lower anxiety and depressive symptoms and better HRQoL on all domains and symptom scales. This was the case for moderate and heavy amounts of alcohol and mostly for consuming beer and wine, but not for liquor. Associations were more often significant for men and for younger persons (< 67 years at baseline).
Generally, alcohol consumption was observed to be longitudinally related to less anxiety and depression and better HRQoL in CRC survivors and the authors conclude that although alcohol consumption is generally unfavourable due to increased risk of carcinogenesis and worse prognosis after CRC, it seems to be associated with better psychosocial outcomes in the first 2 years after diagnosis and treatment. More research is needed to gain knowledge about reasons for drinking and causality.
Source: Révész D, Bours MJL, Wegdam JA, Keulen ETP, Breukink SO, Slooter GD, Vogelaar FJ, Weijenberg MP, Mols F. Associations between alcohol consumption and anxiety, depression, and health-related quality of life in colorectal cancer survivors. J Cancer Surviv. 2022 Oct;16(5):988-997. doi.org/10.1007/s11764-021-01090-y.