Association between wine consumption with cardiovascular disease and cardiovascular mortality

A systematic review and meta-analysis sought to examine the association between wine consumption and cardiovascular mortality, cardiovascular disease (CVD), and coronary heart disease (CHD) and secondly, to analyse whether this association could be influenced by personal and study factors, including the participants’ mean age, the percentage of female subjects, follow-up time and percentage of current smokers.
In order to conduct this systematic review and meta-analysis, several databases were searched for longitudinal studies from their inception to March 2023.
This systematic review included 25 studies and 22 studies were included in the meta-analysis. The pooled RR for the association of wine consumption and the risk of CHD was 0.76 (95% CIs: 0.69, 0.84), for the risk of CVD was 0.83 (95% CIs: 0.70, 0.98), and for the risk of cardiovascular mortality was 0.73 (95% CIs: 0.59, 0.90).
This research revealed that wine consumption has an inverse relationship to cardiovascular mortality, CVD, and CHD. Age, the proportion of women in the samples, and follow-up time did not influence this association. Interpreting these findings with prudence was necessary because increasing wine intake might be harmful to individuals who are vulnerable to alcohol because of age, medication, or their pathologies, the authors say.
Source: Lucerón-Lucas-Torres M, Saz-Lara A, Díez-Fernández A, Martínez-García I, Martínez-Vizcaíno V, Cavero-Redondo I, Álvarez-Bueno C. Association between Wine Consumption with Cardiovascular Disease and Cardiovascular Mortality: A Systematic Review and Meta-Analysis. Nutrients. 2023; 15(12):2785.