Association between alcohol intake pattern and metabolic syndrome components and simulated change by alcohol intake reduction

A study investigated the association between alcohol intake pattern and metabolic syndrome (Mets) components and simulated the change in the prevalence of Mets components by intake reduction.
In order to manage Mets, alcohol intake reduction with moderation of intake pattern is required. However, evidence investigating the comparative impact of alcohol intake reduction in amount and frequency for Mets components is limited.
A large-scale cross-sectional study was conducted in the general Japanese population. The study subjects included 37,371 non-drinkers and current drinkers recruited in the Japan Multi-Institutional Collaborative Cohort Study. Odds ratios (ORs) for Mets components according to alcohol intake amount and frequency were estimated using multiple logistic regression model. The prevalence of Mets components was estimated after assumed alcohol intake reduction of (a) none, (b) 10 g/day (men) or 5 g/day (women), (c) 20 g/day (men) or 10 g/day (women), (d) less than 20 g/day (men) or 10 g/day (women) for moderate-to-heavy drinkers, (e) 1-2 times/week, and (f) 3-4 times/week.
The ORs with alcohol intake amount and frequency increased on high blood pressure and decreased on dyslipidemia. A J-shaped association was observed between intake amount and Mets. The estimated prevalence (%) of high blood pressure and dyslipidemia in men were (a) 45.2, (b) 43.0, (c) 41.4, (d) 40.4, (e) 42.9, and (f) 42.0 and (a) 50.3, (b) 51.8, (c) 52.9, (d) 50.2, (e) 52.7, and (f) 53.4, respectively. The estimated prevalence of high blood pressure in women did not evidently decrease.
Simulated alcohol intake reduction to moderate levels showed decreased prevalence for high blood pressure and increased prevalence for dyslipidemia in men after reduced intake amount and frequency. The largest decreased prevalence for high blood pressure was observed in men when heavy drinkers reduced their alcohol intake amount to less than 20 g/day.
Source: Ippei Shimoshikiryo, et al.,Association between alcohol intake pattern and metabolic syndrome components and simulated change by alcohol intake reduction: A cross-sectional study from the Japan Multi-Institutional Collaborative Cohort Study, Alcohol, 2020, ISSN 0741-8329.