Alcohol intake and the risk of glioma

The association between alcohol intake and the risk of glioma has been widely studied, but these results have yielded conflicting findings. Researchers conducted a systematic review and updated meta-analysis to systematically evaluate the association between alcohol intake and the risk of glioma.
A systematic literature search of relevant articles published in PubMed, Web of Science, CNKI and Wan fang databases up to December 2021 was conducted. A total of eight articles with three case-control studies involving 2,706 glioma cases and 2,189,927 participants were included in this meta-analysis.
A reduced risk of glioma was shown for the low-moderate alcohol drinking versus non-drinking (RR=0.87; 95%CI:0.78, 0.97). In addition, there was no evidence of an increased risk of glioma in the heavy alcohol drinking compared with non-drinking (RR=0.89; 95%CI: 0.67, 1.18).
The findings suggest an inverse association between low-moderate alcohol drinking and the risk of glioma. The authors comment however that in the absence of a dose-response relation-ship, more prospective studies are needed to provide further insight into the association between alcohol drinking and glioma risk.
Source: Shu, L., Yu, D., & Jin, F. (2022). Alcohol intake and the risk of glioma: A systematic review and updated meta-analysis of observational study. British Journal of Nutrition, 1-9.