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Effects of white wine consumption on weight in rats: Do polyphenols matter?

The effects of white wine and the role of wine polyphenols on weight gain in rats of different age were examined in the 4-week-voluntaryconsumption trial.

The effect of a standard white wine, low in polyphenols, and macerated high polyphenolic content white wine were compared. One- and threemonth- old Sprague-Dawley male rats (n = 78) were used. Each age group was subdivided into wateronly- drinking controls (C), standard wine, and high polyphenolic content wine-drinking animals. Daily wine and total liquid consumption, food intake, and body weight were measured, and energy intake and feed efficiency index were calculated.

In both age categories, all wine-drinking animals consumed less food and gained less weight in comparison to the controls (181 ± 2, 179 ± 6, and 201 ± 5 in younger animals and 32 ± 5, 28 ± 6, and 47 ± 4 grams in older animals, resp.), regardless of wine type. Total energy intake was the lowest in high polyphenolic content wine-drinking animals.

Wine-drinking animals gained less weight in comparison to controls, regardless of the wines’ polyphenol content.

The authors state that although the results of this study are indicative of the major role of nonphenolic constituents of the wines (probably ethanol), the modifying role of wine phenolics on weight gain cannot be excluded as the group consuming high polyphenolic content wine had lower total energy intake than other groups.

Source: Effects of White Wine Consumption on Weight in Rats: Do Polyphenols Matter? Milat AM, Mudni? I, Grkovi? I, Klju?evi? N, Grga M, Jer?i? I, Juri? D, Ivankovi? D, Benzon B, Boban M. Oxid Med Cell Longev. 2017;2017:8315803. doi: 10.1155/2017/8315803. Epub 2017 Oct 31.

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